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What to actually do about it The strongest evidence for what changes the body composition equation comes from a randomized, head-to-head, placebo-controlled trial published by Lundgren and colleagues in NEJM in 2021

In the STEP clinical trial program, participants receiving Wegovy lost an average of approximately 15 percent of their body weight over 68 weeks
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10.1016/j.bbrc.2009.01.003 172

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