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Semaglutide can influence how your body handles fluid balance, but the relationship between GLP-1 therapy and water retention is more nuanced than simple yes or no

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Discover what clinical trials reveal about mood changes and depression risk during semaglutide treatment

Experts say patients may still have options, but availability and affordability could become more challenging.

The Seattle-based tech giant launched its own GLP-1 program Tuesday aimed at streamlining access to weight loss drugs, with primary care, upfront pricing and doorstep delivery.

Participants received diet (500kcaldeficit per day) and exercise counseling during 2-week run-in, before being randomly assigned (with a telephone or web-based system) to once-daily subcutaneous liraglutide (1.2, 1.8, 2.4 or 3.0mg, n=9095), placebo (n=98) or open-label orlistat (120mg 3, n=95)