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In this pooled analysis of orforglipron Phase 3 clinical trials, orforglipron treatment was not associated with drug-induced liver injury, demonstrating a hepatic safety profile similar to placebo or active comparators

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A clinician will evaluate your current dose, health conditions, and weight-loss goals before recommending a transition to ensure safety and effectiveness

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doi: 10.2337/diabetes.48.12.2270 [DOI] [PubMed] [Google Scholar] 130

TZP decreases serum alanine aminotransferase and atherogenic biomarkers (chylomicrons, small dense LDL-cholesterol levels, apoB, apoC-III) (57)