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John Eng, an endocrinologist at the Bronx VA Medical Center, discovered a hormone in that venom called exendin-4

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This broader mechanism may explain why retatrutide has shown especially strong weight loss results in early trials, though semaglutide currently has the advantage of regulatory approval and longer-term real-world data

Most common side effects are stomach-related: Nausea (the most frequent complaint) Diarrhea Vomiting Constipation These symptoms usually happen in the first few weeks of treatment and improve over time

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With both medications now widely available through telehealth, patients are asking the obvious question: which one is right for me