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This hollowed-out appearance is not uncommon among people who lose a lot of weight rapidly

S.Bajwa-JosephM.LetchfordD.ChowdhuryK.et al (2017)

C., Chen, J
Changes to your microbiome could theoretically affect vitamin K production and, by extension, the efficacy of blood thinners like warfarin

[DOI] [PubMed] [Google Scholar] 17.Waldrop G, Zhong J, Peters M, Rajagopalan S
Compared with the overweight/obese reference group, which had a rate of major birth defects irrespective of aetiology of 6.3%, the crude OR was 0.66 (95% CI, 0.21 to 2.07), and the adjusted OR was 0.60 (95% CI, 0.16 to 2.21)
