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Discussion In the current study, we found a significant association between GLP-1RAs and cholelithiasis

These findings collectively emphasize that while GLP-1RAs are effective in reducing FBM, strategies to preserve or enhance SMM, such as resistance training and adequate protein intake, should be integral to obesity management

According to FDA labeling, tirzepatide has not been studied in patients with a history of pancreatitis, and alternative therapies should be considered for these patients

doi: 10.1007/s12035-009-8059-y, PMID: [DOI] [PubMed] [Google Scholar] 18.Fazio P, Svenningsson P, Cselenyi Z, Halldin C, Farde L, Varrone A

doi:10.1056/NEJMoa1105816 Greenway FL