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DPP-4 inhibitors can be used as monotherapy when metformin is contraindicated or not tolerated

Notice that switching from 5 mg q1wk to 10 mg q2wk decreases cost by 50% and maintains 95% of weight loss

These results demonstrate the potential of GLP-1RAs not only to promote weight loss and metabolic improvement but also to act directly on the hypothalamic inflammation

It mimics hormones that regulate appetite and blood sugar levels, leading to increased insulin production, reduced cravings, and a natural sense of fullness, helping individuals maintain a lower calorie intake

The combined benefits of reduced appetite, increased satiety, slower gastric emptying, and improved blood sugar control make GLP-1 therapy an effective weight loss solution, particularly for individuals who have found it challenging to lose weight with diet and exercise alone

Effect of acarbose, pectin, a combination of acarbose with pectin, and placebo on postprandial reactive hypoglycaemia after gastric surgery