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Further investigations are needed to elucidate the effects of GLP-1RA on the disease process, joint structure and [patient reported outcomes] of OA.

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Each condition must be evaluated individually based on its specific pathophysiology and how it might interact with GLP-1/GIP receptor agonism

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The main pharmacological efficacy biomarkers determined in Phase 3 studies for GLP-1 RAs are summarized in Table 4

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Rao advises

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HRT nausea is more common with oral delivery

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