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Description
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Oral tirzepatide can interact with certain medications, including oral contraceptives, and may require dosage adjustments for other diabetes medications like insulin or sulfonylureas

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The C-terminus is amidated, which contributes to enhanced metabolic stability and reduced susceptibility to carboxypeptidase degradation

Abdominal discomfort and bloating may cause patients to alter their dietary habits, potentially reducing fiber intake or fluid consumption, which can worsen constipation
