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This does not mean the medication was a failure

Deicken RF, Pegues MP, Anzalone S, Feiwell R, Soher B

Putting GLP-1 Side Effects Into Perspective Its important to note that although GLP-1s can certainly cause side effects, so can obesity, and the side effects of obesity can often be far more serious than nausea

GLP-1RA Cardiovascular Disease Outcomes Starting in 2008, the FDA began requiring all medications indicated for treatment of type 2 diabetes to evaluate cardiovascular risk reduction [45]

a low-fat diet on non-alcoholic fatty liver disease in children: a randomized trial

Tirzepatide, a dual GIP/GLP-1 agonist, carries similar labeling uncertainties