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Safety and efficacy of once-weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes over 84 weeks

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Setmelanotide (Imcivree) licensed for the treatment of obesity caused by specific rare genetic conditions (including pro-opiomelanocortin [POMC] deficiency and leptin receptor deficiency)

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That means overall body composition improved: patients had a higher percentage of lean tissue and a lower percentage of fat after treatment