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Kidney Int 93(4):932940

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This leads to high blood sugar levels, which can cause a range of health issues over time, including heart disease, kidney problems, and nerve damage

Rare but serious side effects may include kidney problems or kidney failure, gallstones, and inflammation of the pancreas or gallbladder

You may remember that Avandia was actually pulled from the market because of increased heart failure risk, and that this led to a revolution in diabetes care prioritizing cardiovascular safety before diabetes drugs could be FDA approved

Originally developed for managing type 2 diabetes, Ozempic (semaglutide) and Mounjaro (tirzepatide) belong to a class of drugs called GLP-1 receptor agonists (Mounjaro also targets a second hormone, GIP)