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Instead, efforts were redirected to develop and assess an improved once-daily formulation aimed at enhancing the drug's tolerability and patient acceptance

The SAFA trial actively tracked side effects across 410 women on 50-100 mg/day

The Clarke error grid illustrates the difference between blood glucose levels determined by the sensor and the commercial glucose meter (data from 6 rats) (Fig

Additive hypoglycemia risk

This tells you what improvements persist after discontinuation
It also noted awareness of fraudulent compounded drugs and dosing errors that led to adverse patient events
