tirzepatide active ingredient hi-res stock photography and images Tirzepatide | C225H348N48O68 | CID

Figure 5: Change in Body Weight (%) After 12-Week Intensive Lifestyle Intervention Lead-In Followed by Randomized Treatment and a Standard Lifestyle Intervention (Study 3) in Patients with Obesity or Overweight Note: Displayed results are from the randomized Population

Supports steady weight loss and energy balance

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Tirzepatide may produce slightly faster results due to its dual mechanism, but both require 16-20 weeks to see substantial weight loss

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These theories all come into play in some of the preclinical studies of GLP-1 RAs in animals, where it was demonstrated that GLP-1 RAs can reduce dopaminergic neuron loss and improve motor function