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Insight: The Mounjaro Effect and Novo Nordisks Strategic Pivot Eli Lilly's dual-action drug, Mounjaro (tirzepatide, marketed as Zepbound for obesity), has been a phenomenal market disrupter

Studies in disease-free individuals show inconsistent results

Do patients regain weight after stopping GLP-1 medications

Past research shows that most people taking a GLP-1 drug can expect to lose between 5% to 15% of their starting body weight over 1 year

Most DA is transported to synaptic vesicle storage pools by vesicular monoamine transporter 2 (VMAT2) on the synaptic vesicle membrane, with a very low cytoplasmic DA concentration (17)