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Conclusion Liraglutide was associated with the highest risk of clinically relevant cholelithiasis than semaglutide, and dulaglutide in patients with T2D.

While neither compound has yet received FDA approval,

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Yerba mate (Ilex paraguariensis), in turn, presents a more moderate caffeine profile, typically containing 0.3% to 1.8% of caffeine in dry weight4, and balanced levels of theobromine and theophylline