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[18] Nature pipeline review

Michael Landzberg (cardiovascular and palliative care faculty and former director of ACHD at Brigham and Womens Hospital)

Step 3: Identify your likely maintenance dose Based on your goals and body weight: Moderate weight loss, lighter body weight: 4 to 8 mg Moderate weight loss, heavier body weight: 8 mg Aggressive weight loss, any body weight: 8 to 12 mg Metabolic health focus: 4 to 8 mg Maximum fat loss with muscle preservation: 4 to 8 mg with high protein intake Step 4: Establish your monitoring protocol At minimum, track weekly body weight (same time, same conditions), side effect type and severity, daily caloric and protein intake, hydration status, and energy levels

Hyman M.D

References 1.Burki T

Most respond well to dose escalation or behavioral intervention