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Initial symptoms peak in weeks 24 and gradually resolve as your digestive system adapts to slower gastric emptying

Consider digestive enzymes Digestive enzymes can help break down food, decreasing the buildup of gas, supporting gut health, and reducing excessive belching

Some real world studies have demonstrated no difference in rates of thyroid cancer between those with diabetes on GLP1RA or on different blood sugar control medications, and some studies have shown some increase in thyroid cancer including medullary thyroid cancer

Microdose protocols are usually slower

The second option is 8 mg/mL tirzepatide with 2 mg/mL niacinamide in a 2.5 mL vial

Last reviewed: June 20, 2026 Last updated: June 20, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations