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GLP-1 medications can suppress thirst signals, meaning you may not feel as thirsty as you actually are

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Clinical trials show patients typically feel fuller faster and experience reduced cravings, often eating 2030% fewer calories without conscious restriction

Thus, a reduction of hyperactivity is often translated to mean a reduction in NAc dopamine release and used as a proxy measure for a reduction of the rewarding/addictive properties of a given psychostimulant

The delayed gastric emptying caused by GLP-1 agonists might theoretically contribute to reduced alcohol consumption by altering absorption kinetics and the subjective experience of intoxication, though this hypothesis requires human pharmacokinetic studies for validation

Ours was among the first, maybe the first study, that was published on GLP-1s in breast cancer, but it was a very small cohort that came out of Memorial Sloan Kettering