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However, GLP-1 RAs can be combined with (basal) insulin in either free- or fixed-dose preparations

After eating, GLP-1 stimulates the pancreas to release insulin, which helps regulate blood glucose levels by facilitating the absorption of sugar into cells

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Serious adverse events including pancreatitis and gallbladder disease have been reported at lower rates across clinical trial populations

The primary distinction between them lies in their active ingredients and mechanisms of action