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Sitagliptin is the first of a class of drugs to be approved that mimics the actions of the dipeptidyl peptidase-4 (DPP-4) enzyme.

Overall, the GLP-1 market is expected to experience annual growth exceeding 20% and will hit $133 billion worldwide by 2030, according to a MarketWatch report from February.
Obesity patients face plan limits, prior authorization requirements, step edits, and non-formulary coverage resulting in a staggering 40% rejection rate and a 48% loss in demand

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