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The impairment of KP in ALS is confirmed by the following evidence: higher serum tryptophan, cerebrospinal fluid (CSF), KYN and QA and a decrease in serum picolinic acid levels in ALS patients

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10.7326/M21-2941 9 ChubbB.GuptaP.GuptaJ.NuhohoS.KallenbachK.OrmeM