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[DOI] [PubMed] [Google Scholar] 61.Zhong J., Rajagopalan S

The peptide crosses the blood-brain barrier and acts on hypothalamic nuclei that regulate hunger

The risks of stopping GLP-1 medications abruptly include not just weight regain but potential withdrawal-like symptoms including rebound hunger and blood sugar fluctuations

Retatrutide activates the same GLP-1 receptors

One of the mechanisms thought to be responsible for weight regain or plateau is a reduction in circulating levels of leptin after initial weight loss [11, 58]

This is a recipe for blood sugar instability
