how long does it take for glp-1 to work Takes Work: Nurse's Timeline Primer: The Skinny on GLP-1s

Over the past few years, there has been an increasing discussion about the potential cardiovascular benefits of sodium-glucose cotransporter 2 inhibitors (SGLT2Is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs)

Semaglutide (Ozempic/Wegovy) is closer to 15%

The side effects are similar to semaglutide GLP-1, primarily gastrointestinal discomfort

Goldstein J, Kirwin J, Seymour N, Trachtenberg J, Rademaker E, Andersen D

By improving insulin regulation and promoting weight loss , GLP-1 medications help restore hormonal balance

However, adding GIP agonism significantly enhances results, suggesting GIP contributes meaningfully to overall weight loss through metabolic effects beyond pure appetite control