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Although EECs might sense nutrients via activation of specific GPCRs on the apical side, where they are in direct contact with the luminal environment, elegantly performed ex vivo and in vitro studies suggest that many nutrients, including fatty acids, may be detected on the basolateral surface 17,93,94

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Its generally recommended for individuals aged 18 to 75, but in specific cases, treatment may begin as early as age 12

BMI is only part of the picture for the cardiovascular risk profile

Add appetite suppression and rapid weight loss to the mix, and those gaps can become more noticeable