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Cagrilintide, a long-acting amylin analogue, is being developed alongside semaglutide 2.4 mg (forming the combination known as CagriSema) for treating T2DM

This mechanism would bypass the gastrointestinal tract and provide steady-state drug levels over an extended period

The 2021 study found that 74 percent of injectable semaglutide users experienced gastrointestinal side effects versus 48 percent of those on placebo

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