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They work by inhibiting glucagon secretion, delaying gastric emptying, and suppressing appetite, which helps regulate blood sugar levels and promote weight loss.However, concerns have been raised in recent years over whether these medications reduce weight mainly via muscle mass loss, which could lead to physical frailty or sarcopenia.Led by assistant professor

- Patients should consult their healthcare provider for proper evaluation, potential drug interactions, and specific dosing instructions tailored to their health conditions

A combination medication like Janumet can be a better choice for people who aren't getting the diabetes management results they need from Metformin alone.