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Diabetes Metab 2017;43(5):4307

One of the most significant side effects of current GLP-1 receptor agonists like semaglutide is nausea possibly linked to how and where these drugs act in the brain

356,357 The activated AMPK pathway can upregulate the expression of FTH1 and GPX4 in intestinal tissues and can improve iron metabolism and redox disorders in the colons of UC rats, thereby effectively treating UC