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Finally, gastrointestinal side effects such as nausea, vomiting, and diarrhea can lead to dehydration and challenged sleep, both of which contribute to exhaustion

PMID: 19403868

For tablet formulations like Rybelsus, storage is simpler

Holz, G

These effects result directly from the medication's mechanism of actionspecifically, delayed gastric emptying and effects on gastrointestinal motility

Compare to the control group, higher expression of p65, IL-6, TNF-, and ratio of p-IB/IB were noted in TG group indicating the activation of NF-B pathway and associated inflammatory response may relate to ER stress
