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"With obesity rates in the UK now at very high levels, and associated with substantial multimorbidity, additional treatment options for sustained weight loss are greatly needed." James O'Loan, chief executive of Chemist4U, said: "The launch of oral weight loss medications is set to be game-changing for UK patients

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Both Rybelsus and Jardiance (empagliflozin) are used to manage type 2 diabetes and promote weight loss, but they work through different mechanisms

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Though microglial activation does have essential housekeeping roles such as removing neuronal cell debris, the chronic overactivation of microglia can cause overproduction of the pro-inflammatory cytokines and dopaminergic neuron degeneration (Ferrari et al., 2006

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