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Li X, Luo W, Tang Y, Wu J, Zhang J, Chen S et al (2024) Semaglutide attenuates doxorubicin-induced cardiotoxicity by ameliorating BNIP3-Mediated mitochondrial dysfunction

We also expand on these findings by showing that KO of CNS GIPR can sensitize the response to GLP-1R agonism and that CNS GIPR is necessary for the maximal weight loss response to mGIPR-Ab/GLP-1

thus, there is a smaller window for weight loss, as body weight defence mechanisms have a greater role in lean mice, potentially confounding the absence of treatment effects

[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Armstrong AW, Read C
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