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Unlike injectable obesity drugs, which are peptides designed to mimic the appetite-controlling GLP-1 hormone, orforglipron is a small molecule pill that is easier to manufacture and package, said Kenneth Custer, president of Lilly's cardiometabolic health division

Mitochondrial TCA cycle metabolites control physiology and disease

Although these data highlight a growing understanding of GLP1 action in the brain, they also raise several questions for future investigation

doi: 10.1016/j.bbr.2018.08.006 [DOI] [PubMed] [Google Scholar] 128.Al Qassab M, Mneimneh M, Jradi A, et al