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As Drucker pointed out to me: We know that GLP-1 is not getting directly to those neurons, but it's activating pathways that turn on those neurons

Brown adipose tissue (BAT

21 Given this critical findings, The ADA advises using GLP-1 RAs to treat type 2 diabetes in adults with MASH, citing histological benefits demonstrated in the mentioned phase 2 randomized controlled trials

Winkler Cohen)

The development of dual GIPRGLP1R coagonists that bind to either one or the other receptor (sequence-mixed dual agonists) has emerged as an innovative therapeutic strategy for obesity and type 2 diabetes

However, he cautioned that its still important to follow the guidelines set by the American Society of Anesthesiologists, and there may be times when the procedure needs to be delayed if too much food is still in the stomach (5)
