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CNN released a comprehensive report highlighting several individuals who were diagnosed with gastroparesis after beginning GLP-1 agonist medications like Ozempic and Wegovy

The owners of this house haven't been seen for days

Also known as stomach paralysis, gastroparesis can be serious if left untreated

OASIS trials: establishing effective doses Phase 2 OASIS 1 findings: Tested multiple dose levels: 0.3mg, 0.6mg, 1.2mg, 2.4mg, 4.5mg weekly Duration: 26 weeks Primary endpoint: Weight loss at each dose Dose-response results: 0.3mg weekly: ~4% body weight loss 0.6mg weekly: ~6% body weight loss 1.2mg weekly: ~8% body weight loss 2.4mg weekly: ~10% body weight loss 4.5mg weekly: ~12% body weight loss Key insight: Clear dose-response relationship

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The medication is 99% protein bound to plasma albumin, which contributes to its relatively long half-life despite being shorter than semaglutide