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10.1124/mol.111.072884 56 KristensenS

Although the overall risk is low, it is a significant concern

10.1111/j.1476-5381.2011.01272.x [DOI] [PMC free article] [PubMed] [Google Scholar] 93.Muscogiuri G, DeFronzo RA, Gastaldelli A, Holst JJ (2017) Glucagon-like Peptide-1 and the Central/Peripheral Nervous System: Crosstalk in Diabetes

No, GLP-1 receptor agonists are not licensed or recommended by NICE, the MHRA, or other UK regulatory bodies for cognitive impairment or dementia

8 This extensive expression of the GLP-1 receptor explains the wide-ranging effects of GLP-1 drugs

In such cases, combination therapy with basal insulin or other agents may be necessary, or alternative treatment approaches might be more appropriate
