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In an era increasingly defined by complex, multifactorial diseases, such systems may be better suited to therapeutic intervention than narrowly targeted pathways optimized for reductionist endpoints

"Muscle matters: the effects of medically induced weight loss on skeletal muscle." The Lancet Diabetes & Endocrinology 12.11 (2024): 785-787

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Here are some of the top options: Berberine Berberine, found in plants like goldenseal and barberry, has been shown to naturally regulate glucose and improve insulin sensitivity

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Hair loss risk Rapid weight loss from any cause can trigger telogen effluvium, a form of temporary hair shedding