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These findings further highlight the transformative potential of retatrutide in improving both metabolic and cardiovascular health

2005;289(5) doi: 10.1152/ajpgi.00121.2005

From targeted oncology therapies to breakthroughs in immunology and metabolic disease, the pace of innovation is accelerating in ways that were difficult to imagine just a few years ago

Feng X, McDonald JM

Summary: Dark urine on Ozempic typically results from dehydration caused by gastrointestinal side effects such as nausea, vomiting, and diarrhoea, leading to concentrated urine rather than being a direct drug effect

We included peer-reviewed randomized controlled trials, meta-analyses, and high-quality narrative or systematic reviews written in English that evaluated the effects of GLP-1 receptor agonists (liraglutide, semaglutide, or related analogues), as well as dual GIP/GLP-1 receptor agonists (such as tirzepatide), exercise training, or their combination on weight loss, body composition, metabolic, or cardiovascular outcomes in adults with obesity or type 2 diabetes