glp-1 drugs pharmaceutical companies news 2025 Lilly is now pharma's top revenue company. It just got FDA approval for an oral GLP-1, but Wall Street isn't celebrating GLP-1 Pipeline Update: November 2025

a systematic review and meta-analysis

Research has extensively explored the effects of endogenous and exogenous GLP-1 on brain activity related to homeostasis and reward systems, particularly in the context of obesity and type 2 diabetes mellitus (T2DM)

The other creates gastrointestinal problems

What do they want to achieve

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The half-life of these drugs varies widely (see table below) from two weeks with the extended-release form of exenatide (Bydureon Bcise), which is injected weekly, to thirteen hours for the daily injected liraglutide (Victoza, Saxenda)