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In a recent study, 44% of people on Wegovy reported feeling more tired than usual

GLP-1 receptor agonists improve MASH mostly via extrahepatic actions: 1 CNS appetite control weight loss systemic inflammation 2 Chylomicron synthesis & improve lipid metabolism 3 Bind gut immune cells anti-inflammatory + microbiome benefits 4 Reduce adipose & pancreatic inflammation

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Darien Sutton discusses a potential once-monthly GLP-1 drug that Pfizer is studying and how it differs from a once-weekly option.