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Anti-inflammatory mechanisms The pain-relieving properties of GLP-1 receptor agonists stem largely from their anti-inflammatory effects in neural tissue
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Many of the classic hormones regulating feeding have a direct impact on the mesolimbic VTA/NAc neurons (Abizaid et al., 2006

Following the success of GLP-1 receptor agonists, pharmaceutical research has shifted toward more complex, multi-hormonal therapies

10.1016/j.regpep.2006.02.007 173
