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SURMOUNT-2 ket efficacy results, source: reference [2] Additionally, 81.6% (10 mg) and 86.4% (15 mg) of people taking tirzepatide achieved at least 5% body weight reduction , the other co-primary endpoint, compared to 30.5% of those taking placebo

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Mitigation strategies include maintaining hydration above 80 ounces per day, consuming soluble fiber (psyllium husk, 510 grams daily), and avoiding high-fat meals that further delay gastric emptying