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Storage 4 C,-20 C Storage Comment Maintain refrigerated at 2-8 C for up to 6 months

The first biosimilar semaglutide products are not expected before the early 2030s at the earliest, and even then, biosimilar pricing typically settles at only 20-40% below the reference product due to the ongoing costs of biologic manufacturing

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Hepatology (2010) 51:158492

This temporal pattern strongly suggests that rapid physiological changes, not gradual fat mass reduction, are driving at least the early component of cardiovascular risk reduction