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This meta-analysis assessed the safety and effectiveness of combinations of SGLT2is+GLP-1RAs with a focus on their cardioprotective effects along with glucose-lowering ability in patients with type 2 diabetes mellitus (T2DM) in a real-world setting

In this review, we summarize the state-of-the-art evidence regarding the epidemiology and pathophysiology of diabetic HFpEF, and the landscape of the novel antidiabetic drugs in the treatment of diabetic HFpEF, as well as discuss the relevant mechanisms, aiming to broaden the understanding of diabetic HFpEF and gain new insight into the treatment of this disease

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Both compounds belong to the growing class of incretin-based weight loss medications that target GLP-1, GIP, and glucagon receptors to help patients lose weight, improve blood sugar control, and reduce liver fat

Weight loss injections like Saxenda (liraglutide) have surged in popularity all over the county, which is no surprise given the obesity epidemic in

Results Four head-to-head randomized controlled studies with 1755 patients were included