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2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5533623

Both use the same titration schedule starting at 0.25 mg

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J Mater Chem B

The exact approved dosing will be determined by the FDA label when orforglipron is approved

"These studies show that weight loss with Wegovy is predominantly driven by reductions in fat, while muscle function is preserved."
