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Additionally, OSA-induced oxidative stress, systemic inflammation, and endothelial dysfunction promote insulin resistance, contributing to the development of metabolic syndrome and atherosclerosis [15]

After drug discontinuation the patient was treated with adalimumab, cyclosporine, and intralesional steroids [77]

Using NMRI mice, systemic Ex4 (2.4 g/kg, i.p.) attenuated hyperlocomotion induced by cocaine (15 mg/kg, i.p.) and amphetamine (2 mg/kg, i.p.) and abolished drug-evoked increases in extracellular dopamine in the NAc, as assessed via in vivo microdialysis

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