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SURPASS-2: Comparing Tirzepatide to semaglutide, another GLP-1 receptor agonist, this study demonstrated superior glycemic control and weight loss with Tirzepatide

2 GLP-1 RAs reduce major adverse cardiovascular events (MACE), including acute myocardial infarction, stroke, and mortality, in patients with multiple cardiovascular risk factors

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Retail Zepbound at $1,086 a month is $13,032 for the same year

Metformin represents an alternative oral agent with growing evidence for pregnancy safety

Alcohol stimulates gut motility, irritates the GI lining, and can worsen dehydration that is already underway