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Researchers are still studying the effects of GLP-1 RAs during early pregnancy

Estrogens also enhance the expression of glucose transporters GLUT3 and GLUT4 in the brain (Stirone et al., 2005
A recent study further demonstrated that the suppression of hepatic glucose production, measured via the clamp technique using tracer glucose, was accompanied by a reduction in glucagon levels and increased insulin secretion in subjects with type 2 diabetes administered 100 mg of vildagliptin (55)

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