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Description
The treatment (Victoza or placebo) was unblinded after the 26-week visit, and the trial was continued for an additional 26-week open-label extension

These results suggest that CYE-1, CHK-1, and DIV-1 play an important role in GLP-1/Notch-mediated germline proliferation

What Patients Should Ask Before Starting Any GLP-1 or Peptide-Based Weight-Loss Plan Before starting a GLP-1 medication, peptide therapy, or any online product marketed for weight loss, patients should ask: Is this medication FDA-approved or investigational

One known risk with GLP-1s is muscle loss, so at a minimum, resistance training and a protein-rich diet should be encouraged

In the Muscle: GLP-1 Increases glycogen production and glucose oxidation.These actions are in favor of weight reduction, decrease in hyperinsulinemia and increase in insulin sensitivity, offering an indirect cardiovascular protection
Expert Review of Clinical Pharmacology, 17 (8), 721729
