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Originally identified for their role in glucose homeostasis, these compounds have become the primary focus of contemporary longitudinal studies involving obesity, neurodegeneration, and cardiovascular health

Efpeglenatide is a drug in which an exendin-4 analog is linked to a human immunoglobulin G4 fragment through a polyethylene glycol (PEG linker), allowing for Fc receptor of neonate (FcRn)-mediated recycling and reduced excretion through the kidneys [50]