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According to the 2024 World Obesity Report, the global prevalence of obesity is steadily increasing, with projections indicating that by 2035, over half of the world's population will be classified as overweight [1]
They work by activating GLP-1 receptors, which help the body manage glucose levels and improve insulin response after eating

This Topic Guide brings together everything Peter has discussed across podcasts, AMAs, and writing to help you understand how GLP-1 agonists work, what the evidence actually shows, and how to reason clearly about their roleif anyin a sustainable, long-term approach to health.

Amarasate comes from a specific variety of Hops grown in NZ a

The GLP1-RAs vs sodium-glucose cotransporter-2 (SGLT-2) inhibitors cohort included new users of GLP-1 RAs (n=83,464) or SGLT-2 inhibitors (n=78,366), and the GLP1-RAs vs dipeptidyl peptidase-4 (DPP-4) inhibitors cohort included new users of GLP-1 RAs (n=108,322) or DPP-4 inhibitors (n=55,411)
